Nursing Pathophysiology and pharmacology

Nursing Pathophysiology and pharmacology

Mrs is an 80 year old woman awaiting discharge following a left hemiarthroplasty. The nurse observes that she is shivering and complaining of feeling cold but, on examination, has a temp of 38oC. A midstream specimen of urine reveals high levels of leucocytes and nitrites in her urine.

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a) with reference to the underlying pathophysiology explain why she feels cold despite the fact her temp is elevated? 35%
b)what factors have contributed to the risk of her developing a urinary tract infection (UTI) 20%
Mrs is prescribed Trimethoprim 200 mg, BD
c) with reference to the pharmacodynamics and pharmacokinetics discuss the use of Trimethoprim to treat her’s UTI including any risk factors. 35%

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