pathophysiology

ASSIGNMENT DETAILS_x000D_
_x000D_
The ability to communicate your knowledge in oral and written formats is a core academic skill set you should acquire whilst at University._x000D_
Learning Outcomes_x000D_
Successful completion of this assignment should allow you to:_x000D_
– demonstrate an understanding of the pathophysiology, diagnosis and prehospital management of patients with respiratory-related conditions,_x000D_
– apply an integrated understanding of the anatomy and physiology of body systems to paramedic practice,_x000D_
– define and effectively convey clinically relevant information in an organised and logical fashion,_x000D_
– support your viewpoints with sound reference sources and where possible provide a balanced critical assessment of the evidence base used to inform accepted clinical practices,_x000D_
– broaden your understanding of the relationships between body systems and the development of pathology/pathophysiology_x000D_
_x000D_
Assignment Requirements_x000D_
_x000D_
A 1500 word, structured response answering the specific questions presented in the following case study._x000D_
_x000D_
• Information provided in your answers must be referenced following academic conventions. A bibliography should be included at the end of your document conforming to Harvard (author/date) format. References and in text citations are not included in the word count._x000D_
• Diagrams can be included to help support your answers – they are not included in the word count._x000D_
• Use the answer templateprovided by pasting it into a new document_x000D_
Weighting : 15%_x000D_
_x000D_
PARA2001: Integrated Clinical Case_x000D_
_x000D_
Patient Background_x000D_
You have been tasked Priority 2 to a 75 year old man with chest tightness and shortness of breath. On your arrival you find a very thin, elderly man sitting on a chair with his arms braced on his knees. He looks very dyspnoeic. His initial observations are:_x000D_
_x000D_
Respiratory rate 45 breaths/minute_x000D_
Heart rate 120 beats/minute_x000D_
Blood Pressure 95/50 mmHg_x000D_
Oxygen saturation 82%_x000D_
Glasgow Coma Score 13 (E=3,V=4, M=6)_x000D_
_x000D_
The man’s name is Mr Wenham, and he is only able to speak single words. His wife tells you that his breathing is never very good, because he smoked far too much. She says he sometimes struggles to walk around the house._x000D_
_x000D_
Symptoms Shortness of breath, chest tightness, cough_x000D_
Onset “His breathing has been particularly bad for the last two days and much worse for the last hour or so”_x000D_
Chest examination Barrel chested, little chest wall movement_x000D_
Breathing sounds Very quiet breath sounds, occasional wheeze_x000D_
Jugular veins Elevated 5cm_x000D_
_x000D_
You form the view that Mr Wenham is suffering from an exacerbation of Chronic Obstructive Pulmonary Disease (COPD). You administer supplemental oxygen, atrovent and salbutamol (following local guidelines), and prepare for the 60 minute journey to hospital._x000D_
_x000D_
1. Describe the underlying pathology of COPD and the common pathological characteristics of the condition. Discuss the impact these pathological changes have on normal function, including how alveolar ventilation might be different in Mr Wenham compared to a normal individual.(20 marks)_x000D_
_x000D_
2. Discuss why you would administer salbutamol and describe how it works at the cellular level.(10 marks)_x000D_
_x000D_
Mr Wenham’s oxygen saturation improves with supplemental oxygen but he remains tachypnoeic, tachycardic and hypotensive. On arrival at the Emergency Department you go straight to the resuscitation room and an arterial blood gas sample is taken and analysed immediately with the following results:_x000D_
pH 7.12_x000D_
PaO2 100 mmHg._x000D_
PaCO2 110 mmHg_x000D_
HCO3 38_x000D_
3. Discusswhy they would take an arterial blood gas and explain what the results mean and how they relate to the pathophysiology you described.(10 marks)_x000D_
_x000D_
The emergency department staff suggest you may have given Mr Wenham too much oxygen. They say they are going to remove the oxygen._x000D_
_x000D_
4. Discuss the normal control of ventilation and the issues surrounding the use of supplemental oxygen therapy in patients with severe exacerbations of COPD. What problems can it cause and why? (20 marks)_x000D_
_x000D_
5. When considering his blood gas analysis, do you think it is a good idea to remove Mr Wenham’s oxygen and have him just breathing air? Provide an argument supporting why it is OR why it is not.(10 marks)_x000D_
_x000D_
The emergency department consultant returns from his lunch break to interrupt the oxygen debate. He suggests that Mr Wenham needs BiPAP._x000D_
_x000D_
6. What is BiPAP? How might BiPAP help to improve Mr Wenham’s clinical condition? (10 marks)_x000D_
_x000D_
Three days later, after 18 hours of BiPAP, corticosteroids and physiotherapy, Mr Wenham is much improved. The respiratory physician responsible for his care orders spirometry. This shows:_x000D_
FEV1 0.75 litres_x000D_
FVC 1.5 litres_x000D_
FEV1/FVC 50%_x000D_
7. What is spirometry? (5 marks)_x000D_
_x000D_
8. Discuss the significance of the results by examining the differences between Mr Wenham’s spirometry and that of a normal individual? (10 marks)_x000D_
_x000D_
9. How does the pathology of COPD explain these differences? (5 marks)_x000D_
_x000D_
PARA2001: Integrated Clinical Case_x000D_
Answer Template (cut and paste into a new document)._x000D_
1. Describe the underlying pathology of COPD and the common pathological characteristics of the condition. Discuss the impact these pathological changes have on normal function, including how alveolar ventilation might be different in Mr Wenham compared to a normal individual. (20 marks)_x000D_
_x000D_
ANSWER:_x000D_
DIAGRAM? SOURCE/ TITLE_x000D_
_x000D_
2. Discuss why you would administer salbutamol and describe how it works at the cellular level. (10 marks)_x000D_
3. Discuss why they would take an arterial blood gas and explain what the results mean and how they relate to the pathophysiology you described. (10 marks)_x000D_
4. Discuss the normal control of ventilation and the issues surrounding the use of supplemental oxygen therapy in patients with severe exacerbations of COPD. What problems can it cause and why? (20 marks)_x000D_
5. When considering his blood gas analysis, do you think it is a good idea to remove Mr Wenham’s oxygen and have him just breathing air? Provide an argument supporting why it is OR why it is not.(10 marks)_x000D_
6. What is BiPAP? How might BiPAP help to improve Mr Wenham’s clinical condition? (10 marks)_x000D_
7. What is spirometry? (5 marks)_x000D_
8. Discuss the significance of the results by examining the differences between Mr Wenham’s spirometry and that of a normal individual. (10 marks)_x000D_
9. How does the pathology of COPD explain these differences? (5 marks)_x000D_
_x000D_
_x000D_
_x000D_
_x000D_
_x000D_
Do you want your   assignment written by the best essay experts? Click order now, and enjoy an amazing discount._x000D_
REFERENCES_x000D_
APPENDIX